Hi & welcome to the forum!
I can't tell how large the cameo is or what it's made of, so... My recommendations would be to wire wrap the thing in the style of the frame OR consider seed beading around it. I have no idea what your background experiences are so I don't know what skill sets you have or want to acquire. But I don't believe that soldering is an option since you'd have to heat up the entire piece.
If you don't want to wire wrap an elaborate frame, then do a simple prong setting where all the mess is behind, only the prongs show at 4 or 6 places in the front, & the bail comes up from the "prong man" in the back. Good luck!
sher